Centropix ships orders Monday through Friday, excluding public holidays. Next day service orders, placed before 12 pm Eastern, will ship the same day. Carriers typically deliver orders Monday through Friday, excluding public holidays. If your Next Day service order is shipped on Friday, it will arrive on Monday. Please check your carrier’s website for their most recent schedule and any exceptions. Centropix only ships to physical addresses, no PO Boxes. Orders with subtotals greater than $250 will require a signature at delivery.Centropix ships through FedEx and USPS. Please consider signing up for free for FedEx Delivery Manager and USPS Informed Delivery for better visibility and control of your package.